A low-fat may increase the survival rate of obese children with acute lymphoblastic leukemia, known as the most common childhood cancer.
It is found in the research in the University of California, Los Angeles in the US administered the chemotherapy drug vincristine to obese and non-obese mice with leukemia.
The research discovered that if an obese mouse from a high-fat to a low-fat diet immediately before chemotherapy, the mouse had a dramatically improved.
The mice on the low-fat diet had a five times higher survival rate than the mice in the high-fat diet group, the study published in the journal Cancer & Metabolism found.
“The most exciting thing to me about this study is the fact that this shows that a dietary intervention could potentially help us kill leukemia cells in children with acute lymphoblastic leukemia,” said Steven Mittelman from UCLA Mattel Children’s Hospital.
“The current treatments for leukemia are very toxic, so finding a way to use a healthy diet, without increasing the toxicity of therapy to treat people with cancer, would be incredible,” Mittelman added.
The research is based on past work by Mittelman, according to which obesity makes chemotherapy drugs less effective in children with leukemia.
After chemotherapy, obese children with leukemia relapse 50 per cent more often than their lean counterparts.
Source: eletsonline.com
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